METTLE™ 125 ME fungicide is now registered with the California Department of Pesticide Regulation, paving the way for a full introduction in the Golden State in 2009, where it is targeted for use on grapes. Mettle is registered in Oregon, Washington, Ohio and Michigan and is pending in New York and other states. Manufactured and marketed by Isagro USA, METTLE contains the highly active ingredient tetraconazole. This broad-spectrum fungicide belongs to the Sterol Biosynthesis Inhibitor (SBI) class but contains a “tetrafluoroethoxy” group which is unique within the SBI class. This group provides highly systemic properties resulting in improved fungicidal action compared to other SBI compounds. With both preventive and post-infection activity and low active ingredient content to high performance ratio, METTLE provides outstanding and consistent control of targeted diseases including powdery mildew, at lower application rates than other SBI products. Tetraconazole is registered in more than 50 countries. This market leader is used extensively worldwide for disease control in many crops.